The 2001 U.S. Women's Open Golf Championship was the 56th U.S. Women's Open, held May 31 to June 3 at Pine Needles Lodge and Golf Club in Southern Pines, North Carolina. Defending champion Karrie Webb repeated as champion, eight strokes ahead of runner-up Se Ri Pak, the largest margin in 21 years. Webb became the seventh to win consecutive titles at the U.S.
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