State Route 216, also known as SR-216, is a numbered state highway in Tuscaloosa County, Alabama. SR-216 follows the former route of U.S. Highway 11 through eastern Tuscaloosa County. It serves as an alternate route between Bessemer and Tuscaloosa (the other routes being I-20/59 and US 11). The route was commissioned in April 1978 after ALDOT took over the route formerly maintained by Tuscaloosa County as County Road 116.
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