Highway 375 (AR 375, Ark. 375, and Hwy. 375) is a designation for two north–south state highways in Polk County, Arkansas. A western route of 8.09 miles (13.02 km) runs north from US Route 59/US Route 71 (US 59/US 71) at Potter Junction to Highway 8 in Mena. A second route of 11.62 miles (18.70 km) begins at Highway 8 outside of Mena and runs south to County Road 630 in the Ouachita National Forest.
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