Iowa Highway 64 (Iowa 64) is a 64-mile-long (103 km) state highway that runs across two counties in east central Iowa. It begins at an interchange with U.S. Route 151 (US 151) in Anamosa and ends at the Savanna-Sabula Bridge over the Mississippi River near Sabula. It continues through Illinois as Illinois Route 64. The western half of the highway makes up the Grant Wood Scenic Byway.At one time, Iowa 64 spanned the length of the state.
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