Isotria (fiveleaf orchid) is a genus of flowering plants from the orchid family, Orchidaceae. It has two known species, both native to eastern North America. Isotria medeoloides (Pursh) Raf. - eastern North America from New England south along the Appalachians to Georgia and Tennessee; isolated populations in Missouri, Illinois, Michigan, Ohio, Ontario Isotria verticillata (Muhl. ex Willd.) Raf.
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