Dr. Josephat Njuguna Karanja (5 February 1931 – 28 February 1994) was a Vice-President of the Republic of Kenya between 1988 and 1989. He resigned to avoid an ongoing vote-of-no-confidence in the Kenyan Parliament. He was accused by the now late Hon. David Mwenje Member of Parliament for Embakasi Constituency of wanting to overthrow President Daniel arap Moi's government by soliciting help from foreign nations.
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