The Manskin Indians were a tribe of Indians who were a part of the Powhatan Confederacy in historic Virginia. From 1620-1750 they are referred to as "Manskin", on several maps, a name derived from Manaskunt. The numerous separate Indian villages shown in the Zuniga Map combined under the rule of Opechancanough, as a result of the pressures of losses from infectious disease and encroachment by the English colonists.
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