Mississippi Highway 2 (MS 2) is a designation for three highways in northern Mississippi. The westernmost segment starts at MS 5 in Hickory Flat, and ends at MS 15 and MS 368 in Blue Mountain. The central segment begins at MS 4 east of Ripley, and terminates at U.S. Route 72 (US 72) west of Corinth. The easternmost segment starts at US 45 in Corinth, and ends at the Tennessee state line. The road continues as Tennessee State Route 22 (TN 22).
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