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Profadol (CI-572) is an opioid analgesic which was developed in the 1960s by Parke-Davis. It acts as a mixed agonist-antagonist of the μ-opioid receptor. The analgetic potency is about the same as of pethidine (meperidine), the antagonistic effect is 1/50 of Nalorphine.

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  • Profadol (CI-572) is an opioid analgesic which was developed in the 1960s by Parke-Davis. It acts as a mixed agonist-antagonist of the μ-opioid receptor. The analgetic potency is about the same as of pethidine (meperidine), the antagonistic effect is 1/50 of Nalorphine.
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ATC prefix
  • none
CAS number
  • 428-37-5
FDA UNII code
  • 41GDG43FTT
IUPAC name
  • 3-(1-methyl-3-propyl-pyrrolidin-3-yl)phenol
PubChem
  • 9882
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