U.S. Route 166 (US 166) is a 164-mile (264 km) west–east United States highway. This route and US-266 are the only two remaining spurs of historic U.S. Route 66 (which was decommissioned in 1985), since US-666 was renumbered to US-491 in 2003.US-166 meets the old route of US-66, now designated US-69 Alternate, in Baxter Springs in the southeast corner of Kansas.
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