Virginia State Route 143 (SR 143) is a primary state highway in the U.S. state of Virginia. The state highway runs 35.39 miles (56.95 km) from Camp Peary near Williamsburg east to U.S. Route 258 (US 258) at Fort Monroe in Hampton. SR 143 is a major local thoroughfare on the Virginia Peninsula portion of the Hampton Roads metropolitan area. The state highway is named Merrimac Trail through the independent city of Williamsburg and adjacent portions of York County and James City County.
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