West Virginia Route 480 (WV 480) is a state highway in the U.S. state of West Virginia. Known for most of its length as Kearneysville Pike, the state highway runs 5.6 miles (9.0 km) from WV 115 in Kearneysville north to the Maryland state line at the Potomac River in Shepherdstown, where the highway continues as Maryland Route 34 (MD 34).
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