The 1981 LPGA Championship was the 27th LPGA Championship, played June 11–14 at Jack Nicklaus Golf Center at Kings Island in Mason, Ohio, a suburb northeast of Cincinnati. Donna Caponi sank a 15-foot (5 m) birdie putt on the final green to win her second LPGA Championship, a stroke ahead of runners-up Jerilyn Britz and Pat Meyers. It was Caponi's fourth and final major title.