21 and Wake-Up is a 2009 American war film starring Amy Acker, Danica McKellar, Faye Dunaway, and was directed and written by producer, director, and writer Chris McIntyre.21 and a Wakeup is the first American film about the Vietnam war allowed to shoot on location in Vietnam after the Vietnam War. It is based on a dozen true stories, most surrounding the final days of the 24th Evacuation Hospital, the last major Army hospital in the south to close as Americans abandoned Southeast Asia.