State Route 118 (SR-118) is a state highway in the northwestern part of the U.S. state of Alabama. It is a 57.4-mile-long (92.4 km) route. Prior to the completion of sections of Interstate 22 (I-22), SR-118 served only as the unsigned partner route of U.S. Route 278 (US-278) between the Mississippi state line, west-southwest of Sulligent, and Guin.