The Audio MIDI Setup utility is a program that comes with the Mac OS X operating system for adjusting the computer's audio input and output configuration settings and managing MIDI devices.It was first introduced in Mac OS X 10.5 Leopard as a simplified way to configure MIDI Devices. Users need to be aware that prior to this release, MIDI devices did not require this step, and it mention of it might be omitted from MIDI devices from third-party manufactures.