Avipoxvirus is a member of the Poxviridae family. The Poxviridae family is the family of viruses which cause the victim organism to have poxes as a symptom. Poxviruses have generally large genomes, and other such examples include smallpox and monkeypox. Members of the avipoxvirus genus infect specifically birds. Avipoxviruses are unable to complete their replication cycle in non avian species.