For their albums, and other meanings, see Bone Brothers (disambiguation).Bone Brothers is an American hip hop duo composed of Bone Thugs-n-Harmony members Layzie Bone and Bizzy Bone. The first Bone Brothers album was released in 2005. Bizzy Bone had parted ways from the group in 2003 over personal differences and business decisions. Bizzy Bone had always remained friendly with the group and collaborating in songs such as Lil Eazy's This Ain't A Game and Krayzie Bone's Getchu Twisted Remix.