Brian Lee Keyser (born October 31, 1966 in Castro Valley, California) is a retired Major League Baseball pitcher. He played during two seasons at the major league level for the Chicago White Sox. He was drafted by the White Sox in the 19th round of the 1989 amateur draft. Keyser played his first professional season with their Class A (Short Season) Utica Blue Sox in 1989, and his last season with the Cincinnati Reds' Triple-A club, the Indianapolis Indians, in 1998.