The CANT 22 was a flying boat airliner built in Italy in the 1920s and operated by SISA on their Adriatic routes. It was a conventional biplane design with unstaggered wings braced by Warren trusses. The three engines were mounted in nacelles carried in the interplane gap. Accommodation for passengers was provided within the hull, but the pilots sat in an open cockpit. Originally designed to carry eight passengers, an engine upgrade on later examples allowed the addition of two more seats.