Calgary Trail is a major one-way arterial road in south Edmonton, Alberta, Canada. It is a major commuter route for communities south of Edmonton, such as Leduc.The road begins at Saskatchewan Drive in Old Strathcona as 104 Street, which runs as a two-way street until it reaches University Avenue. It continues in a southbound direction to 55 Avenue, when it becomes Calgary Trail. At Whitemud Drive, Highway 2 follows Calgary Trail.