Chartreuse (pronounced: [ʃaʁtʁøz]) is a French liqueur made by the Carthusian Monks since 1737 according to the instructions set out in a manuscript given to them by François Annibal d'Estrées in 1605. It is composed of distilled alcohol aged with 130 herbs, plants and flowers. The liqueur is named after the Monks' Grande Chartreuse monastery, located in the Chartreuse Mountains in the general region of Grenoble in France.