The Chenango Canal was a towpath canal built and operated in the mid-19th century in Upstate New York in the United States. It was 97 miles long and for much of its course followed the Chenango River, along Rt. 12 N-S from Binghamton on the south end to Utica on the north end. It operated from 1834 to 1878 and provided a significant link in the water transportation system of the northeastern U.S., connecting the Susquehanna River to the Erie Canal.