Chisholm is a city in Saint Louis County, Minnesota, United States. The population was 4,976 at the 2010 census.U.S. Highway 169 and State Highway 73 (MN 73) are two of the main routes in Chisholm. Michael A. Jugovich is currently presiding as mayor, and has been since 2006.A mining town on the Mesabi Range, Chisholm was founded by Archibald Mark Chisholm.