Christopher Greene (May 12, 1737 – May 1781) was an American legislator and soldier. He is best known for leading the spirited defense of Fort Mercer in the 1777 Battle of Red Bank, and for leading the African American 1st Rhode Island Regiment during the American Revolutionary War, most notably with distinction in the 1778 Battle of Rhode Island. He was killed in May 1781 by Loyalists, possibly because he was known to lead African American troops.