The Crompton Mill Historic District is a historic district encompassing a mill complex at 20 Remington Street, 53 and 65 Manchester Street in West Warwick, Rhode Island. The mill complex consists of a collection of mainly brick buildings, bounded by the Pawtuxet River and Pulaski, Remington, and Manchester Streets in the village of Crompton. The mill complex formerly extended across the river, but the complex on the west bank was destroyed by fire in 1992.