Dan Sane (September 22, 1896 – February 18, 1956) was an American Memphis and country blues guitarist and songwriter. He was a working associate of Frank Stokes and, according to Allmusic journalist, Jason Ankeny, "they had emerged among the most complementary duos in all of the blues, with Sane's flatpicking ideally embellished by Stokes' fluid rhythms." The best known of Sane's penned songs were "Downtown Blues" and "Mr. Crump Don't Like It." His surname was alternatively spelt as 'Sain'.