David B. Poythress (born October 24, 1943) is a Georgia politician, born in Bibb County, Georgia. He has served terms as Secretary of State and Commissioner of Labor of the state of Georgia. Poythress also served as the Adjutant General of the Georgia National Guard from 1999 until 2007, initially appointed by Governor Roy Barnes and subsequently reappointed by Governor Sonny Perdue. He retired as a Lieutenant General.In 1998, Poythress made an unsuccessful bid for Governor of Georgia.