Delaware Route 20 (DE 20) is an east–west highway in Sussex County, Delaware. Its western terminus is the Maryland state line in Reliance, where it continues as Maryland Route 392 (MD 392). Its eastern terminus is DE 54 west of Fenwick Island. The route runs through rural areas of Sussex County and passes through the towns of Seaford, Millsboro, and Dagsboro. DE 20 intersects U.S.