Duffields Depot is a former Baltimore and Ohio Railroad station on the National Register of Historic Places, located in the village of Duffields, West Virginia, near Shenandoah Junction. Built in 1839, the depot is the second oldest surviving B&O depot. Only the Ellicott City Station in Ellicott City, Maryland is older. The depot and its enviroins were a significant focus of activity during the American Civil War, culminating in the "Greenback Raid" of 1864.