Eli Cook (1814–1865) was Mayor of the City of Buffalo, New York, serving 1853 and 1854–1855. He was born in Palatine Bridge, New York on January 23, 1814. He took up law in 1830, passed the bar exam, and in 1837 he practiced in Tennessee and Mississippi with rebel General Simon B. Buckner. In 1838, he moved to Buffalo where he became one of the leading criminal lawyers. He married around 1838, but his wife died soon after; he re-married in 1843, to Sarah L.