Elizabeth de Vere, Countess of Derby, Lord of Mann (2 July 1575 – 10 March 1627), was an English noblewoman and the eldest daughter of the Elizabethan courtier, poet, and playwright Edward de Vere, 17th Earl of Oxford.She was the Lord of Mann from 1612 to 1627, and prior to holding the title, she had taken over many administrative duties appertaining to the Isle of Man's affairs.