Euston Road is an important thoroughfare in central London, England, and forms part of the A501. It was originally the central section of the New Road from Paddington to Islington, opened in 1756, London's first bypass, through the fields to the north of London, now generally regarded as being in central London.The road runs from west to east from Marylebone Road to Pentonville Road. It meets the northern end of Tottenham Court Road at a large junction where there is an underpass.