State Road 273 (SR 273) is a north-south highway in the panhandle in the U.S. state of Florida that extends from State Road 77 (SR 77) in Chipley to U.S. Route 231 (US 231) in Campbellton. SR 273 runs through both Washington and Jackson counties, and most, if not all of the road is a two-lane undivided highway. Between its termini, SR 273 intersects with no state roads other than former ones. A former section of the road south of Chipley is now County Road 273.