Frank Harold Spedding (October 22, 1902 – December 15, 1984) was a Canadian American chemist. He was a renowned expert on rare earth elements, and on extraction of metals from minerals. His uranium extraction process helped make it possible for the Manhattan Project to build the first atomic bombs.A graduate of the University of Michigan and University of California, Berkeley, Spedding became an assistant professor and head of the department of physical chemistry at Iowa State College in 1937.