George Francis Pyne III (born July 12, 1941) is a former American football defensive tackle who played one season with the Boston Patriots of the American Football League. He was drafted by the Boston Patriots in the sixteenth round of the 1965 AFL Draft. He played college football at Olivet College and attended Milford High School in Milford, Massachusetts. Pyne's father George Pyne II and son Jim Pyne both played in the NFL.