Geronimo Creek is a stream in South Central Texas, U.S., that runs approximately 17 miles, from its source one mile east of Clear Springs, Texas (in the Texas Prairielands), to its confluence with the Guadalupe River in Guadalupe County, Texas, three miles southeast of Seguin.The creek serves as a tributary of the Guadalupe River and forms its watershed near Seguin, Texas, within the larger Guadalupe River Basin.