Giovanni Gussone (8 February 1787, Villamaina – 14 January 1866, Naples) was an Italian academic and botanist, remembered for his work in plant taxonomy and his research of Sicilian flora.He studied medicine in Naples, where he came under the influence of botanist Michele Tenore. Following graduation in 1811, he worked under Tenore as a manager of the Orto Botanico di Napoli (botanical garden in Naples).