The Grand Valley AVA is an American Viticultural Area located in Mesa County, Colorado, surrounding the cities of Grand Junction and Palisade. The AVA is defined as the irrigated agricultural area served by canals within the Grand Valley of the Colorado River.The AVA encompasses 32,000 acres (13,000 ha). The terrain is varied, ranging from alluvial soils along the Colorado River to stony and loamy soils on mesas.