Great Bend is a borough in Susquehanna County, Pennsylvania, United States, 39 miles north of Scranton. According to 2010 Census data, Great Bend's population was 734, up 4.7% from 2000. Great Bend sits along the Susquehanna River, less than two miles from the New York State border. Located directly off Interstate 81, tourism is a driving force of the area's economy. Several small manufacturers also call Great Bend home.