"Grew Up a Screw Up" is the second single from Ludacris' Release Therapy. The song features Young Jeezy, who Ludacris was previously thought to have beef with and a sample of the late The Notorious B.I.G. who sings the hook "I grew up a fucking screw up."Curiously, in the video, Young Jeezy raps a verse different from the one which appeared on the Release Therapy Disc. The video premiered on BET's 106 & Park as a New Joint on Friday October 13, 2006.