Guided Mouse-ille (or Science on a Wet Afternoon) is a 1967 Tom and Jerry cartoon, produced by Chuck Jones and directed by Abe Levitow. It was the second of three space-age Tom and Jerry shorts to be released in the Chuck Jones era (along with O-Solar Meow and Advance and Be Mechanized), though taking a look at the MPAA code at the beginning of the cartoon would suggest that Guided Mouse-ille (or Science on a Wet Afternoon) was the first of the three cartoons to be produced.