Guided Muscle is a 1955 Warner Bros. cartoon in the Looney Tunes series featuring Wile E. Coyote and The Road Runner.Along with The Grey Hounded Hare and Tugboat Granny, Guided Muscle was one of the three cartoons on the final episode of ABC's The Bugs Bunny & Tweety Show, on September 2, 2000. In fact, it was the last cartoon seen in that episode.