"Hey Ho, What You Do to Me" is a song written by Nickolas Ashford, Valerie Simpson, and Jo Armstead and performed by The Guess Who. It reached #3 in Canada in 1965. The song was released in the United States in August of that same year and reached #125 on the Billboard chart. It was featured on their 1965 album, Hey Ho (What You Do to Me!)The song was produced by Bob Burns and arranged by Chad Allan.