Hugh Othello Wolfe (June 13, 1912 – May 20, 2010) was an American football fullback who played one season with the New York Giants of the National Football League. He was drafted by the Pittsburgh Pirates in the third round of the 1938 NFL Draft. Wolfe first enrolled at John Tarleton Agricultural College before transferring to the University of Texas. He attended Stephenville High School in Stephenville, Texas. He was a member of the New York Giants team that won the 1938 NFL Championship.