The Huisne is a river in France. It is a left tributary of the river Sarthe, which it meets in Le Mans. Its source is near the town Pervenchères, in the Orne department.The Huisne flows through the following départements and towns:Orne: Saint-Jouin-de-Blavou, Rémalard, Condé-sur-Huisne, Le TheilEure-et-Loir: Nogent-le-RotrouSarthe: La Ferté-Bernard, Montfort-le-Gesnois, Le MansOne historic town along the Huisne is Nogent-le-Rotrou.