Huntington Drive is a major east–west street in Southern California. It runs from the merge of Soto Street and Mission Road near the Lincoln Park neighborhood of Los Angeles east through the El Sereno section of Los Angeles, South Pasadena, San Marino, Alhambra, San Gabriel, Arcadia, Monrovia, ending in Duarte. It is also known as Historic Route 66 east of its junction with Colorado Place in Arcadia, until its name changes to Foothill Boulevard at the San Gabriel River.