Interstate 359 (I-359) is a part of the Interstate Highway System in the US state of Alabama. It is a spur route that runs for 2.76 miles (4.44 km) entirely within the city limits of Tuscaloosa. Its termini are just south of I-20/I-59 interchange on the south side of town and U.S. Highway 43 (US 43) in downtown Tuscaloosa. The entire length is concurrent with U.S.