Interstate 75 (I-75) is a major Interstate Highway in the Great Lakes and Southeastern regions of the United States. As with most interstates that end in a five, it is a major cross-country, north-south route, one of the longest in the U.S., from southern Florida to the northern tip of Michigan. It travels from State Road 826 (Palmetto Expressway) and State Road 924 (Gratigny Parkway) on the Hialeah–Miami Lakes border (northwest of Miami, Florida) to Sault Ste.