Interstate 990 (I-990) is an auxiliary Interstate Highway located entirely within the town of Amherst in Erie County, New York, in the United States. It runs in a roughly north–south direction for 6.43 miles (10.35 km) through the southwestern and central parts of Amherst from an interchange with I-290 north of Buffalo to an intersection with New York State Route 263 (NY 263, named Millersport Highway) south of Lockport.